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Information pursuant to Sect. 5 German Telemedia Act (TMG)

GENERATE e.V. vertreten durch PD Dr. Frank Leypoldt
c/o UKSH, Institut für Klinische Chemie und Klinik für Neurologie
24105 Kiel

Register of Associations: 5724
Registration court: Amtsgericht Münster

Represented by:
Vertreten durch Vorstand: PD Dr. Frank Leypoldt und PD Dr. Nico Melzer


Phone: 0431-500-16209
Telefax: 0431-500-16204

Responsible for the content according to Sect. 55, paragraph 2 RStV

GENERATE e.V. vertreten durch PD Dr. Frank Leypoldt
c/o UKSH, Institut für Klinische Chemie und Klinik für Neurologie
24105 Kiel

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Purpose of this website

This website provides information about autoimmune encephalitides and related diseases. It additionally posts evidence relating to diagnosis and therapy. Another aim of this website is to make it easier for the website visitor to find centers specialized in autoimmune encephalitis.
The content offered on this website is intended for the colleagues invested in the GENERATE network, interested members of the medical community and, of course, for the patients and their relatives affected by these diseases. The content posted on is only designed to foster, not replace the relationship between patients/website visitors and their physicians.

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The website does not post nor is it financially sponsored by advertising or commercial ads.


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Latest news

Aktuelle Impfempfehlung (SARS-CoV-2) des GENERATE Netzwerkes vom 07.05.2021

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Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABAA receptor encephalitis

Brändle SM, Cerina M, Weber S et al. PNAS March 2, 2021 118 (9) e1916337118.

Dieses Paper wurde vom Research4Rare Verbund zum Paper of the Month gewählt und erscheint im April dieses Jahres im BMBF Newsletter!

A Therapeutic Non-self-reactive
SARS-CoV-2 Antibody
Protects from Lung Pathology
in a COVID-19 Hamster Model

Kreye J, Momsen Reincke S, Kornau HC et al.
Cell. 2020 Nov 12;183(4):1058-1069.e19.

CD8+ T-Lymphocyte–Driven Limbic
Encephalitis Results in Temporal Lobe

Pitsch J, van Loo KMJ, Gallus M et al.
Ann Neurol. 2021; 00:1-20.

Low CSF CD4/CD8+ T-cell proportions are associated with blood-CSF barrier dysfunction in limbic encephalitis.

Hansen N, Schwing K, Önder D, et al. Epilepsy Behav. 2020;102:106682.

An expanded parenchymal CD8+ T cell clone in GABAA receptor encephalitis.

Bracher A, Alcalá C, Ferrer J, et al. Ann Clin Transl Neurol. 2020;7(2):239‐244.

Routine diagnostics for neural antibodies, clinical correlates, treatment and functional outcome

Bien CG, Bien CI, Dogan Onugoren M, et al. [published online ahead of print, 2020 Apr 3] [published correction appears in J Neurol. 2020 May 12;:]. J Neurol. 2020;10.1007/s00415-020-09814-3.